FLNB Antikörper

Produktnummer ABIN7114241

Der Kaninchen Polyklonal Anti-FLNB-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, FLNB in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für FLNB Antikörper (ABIN7114241)

Target: FLNB (Filamin B, beta (FLNB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLNB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-FLNB Antikörper

Verwendungszweck: FLNB antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: filamin B, beta (actin binding protein 278)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:1000, IHC: 1:20 - 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu FLNB

Target: FLNB (Filamin B, beta (FLNB))

Andere Bezeichnung: FLNB

Hintergrund:

Synonyms: Filamin-B (FLN-B)|ABP-278|ABP-280 homolog|Actin-binding-like protein|Beta-filamin|Filamin homolog 1 (Fh1)|Filamin-3|Thyroid autoantigen|Truncated actin-binding protein (Truncated ABP)|FLNB|FLN1L|FLN3|TABP|TAP

Background: This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Molekulargewicht: 298 kDa

Gen-ID: 2317

UniProt: O75369

Pathways: Maintenance of Protein Location