Fibromodulin Antikörper
Kurzübersicht für Fibromodulin Antikörper (ABIN7114223)
Target
Alle Fibromodulin (FMOD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- FMOD antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- fibromodulin
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- Fibromodulin (FMOD)
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Andere Bezeichnung
- FMOD
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Hintergrund
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Synonyms: Fibromodulin (FM)|Collagen-binding 59 kDa protein|Keratan sulfate proteoglycan fibromodulin (KSPG fibromodulin)|FMOD|FM|SLRR2E
Background: Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.
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Molekulargewicht
- 45 kDa
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Gen-ID
- 2331
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UniProt
- Q06828
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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