FAM20C Antikörper (AA 102-330)

Produktnummer ABIN7114089

Dieses Anti-FAM20C-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FAM20C in WB, ELISA und IHC. Geeignet für Human, Ratte und Maus.

Kurzübersicht für FAM20C Antikörper (AA 102-330) (ABIN7114089)

Target: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM20C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-FAM20C Antikörper

Bindungsspezifität: AA 102-330

Verwendungszweck: FAM20C antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 102-330 aa

Immunogen: family with sequence similarity 20, member C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu FAM20C

Target: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Andere Bezeichnung: FAM20C

Hintergrund:

Synonyms: Extracellular serine/threonine protein kinase FAM20C|Dentin matrix protein 4 (DMP-4)|Golgi casein kinase|Golgi-enriched fraction casein kinase (GEF-CK)|FAM20C|DMP4

Background: Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth(PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome(PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity(PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1(PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion(PubMed:26091039).

Molekulargewicht: 50 kDa

Gen-ID: 56975

UniProt: Q8IXL6