FBXO7 Antikörper
Kurzübersicht für FBXO7 Antikörper (ABIN7114054)
Target
Alle FBXO7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Aufreinigung
- Immunogen affinity purified
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- F-box protein 7
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
-
Haltbarkeit
- 12 months
-
-
- FBXO7 (F-Box Protein 7 (FBXO7))
-
Andere Bezeichnung
- FBXO7
-
Hintergrund
- Synonyms:FBX7 Background:Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy(mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
-
Molekulargewicht
- 58.5 kDa
-
Gen-ID
- 25793
-
UniProt
- Q9Y3I1
Target
-