F-Box Protein 3 Antikörper
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- Target Alle F-Box Protein 3 (FBXO3) Antikörper anzeigen
- F-Box Protein 3 (FBXO3)
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser F-Box Protein 3 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- F-box protein 3
- Isotyp
- IgG
- Top Product
- Discover our top product FBXO3 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- F-Box Protein 3 (FBXO3)
- Andere Bezeichnung
- FBXO3 (FBXO3 Produkte)
- Hintergrund
- Synonyms:FBX3 Background:Substrate recognition component of the SCF(SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
- Molekulargewicht
- 48-50kd
- Gen-ID
- 26273
- UniProt
- Q9UK99
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