ENY2 Antikörper

Produktnummer ABIN7113824

Der Kaninchen Polyklonal Anti-ENY2-Antikörper wurde für ELISA validiert. Er ist geeignet, ENY2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ENY2 Antikörper (ABIN7113824)

Target: ENY2 (Enhancer of Yellow 2 Homolog (ENY2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENY2 Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-ENY2 Antikörper

Verwendungszweck: ENY2 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: enhancer of yellow 2 homolog(Drosophila)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu ENY2

Target: ENY2 (Enhancer of Yellow 2 Homolog (ENY2))

Andere Bezeichnung: ENY2

Hintergrund:

Synonyms: Transcription and mRNA export factor ENY2|Enhancer of yellow 2 transcription factor homolog|ENY2

Background: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation(HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles(mRNPs) to the nuclear entrance of the nuclear pore complex(nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.

Gen-ID: 56943

UniProt: Q9NPA8