ELK4 Antikörper

Produktnummer ABIN7113769

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ELK4 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für ELK4 Antikörper (ABIN7113769)

Target: ELK4 (ELK4, ETS-Domain Protein (SRF Accessory Protein 1) (ELK4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ELK4 Antikörper

Verwendungszweck: ELK4 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: ELK4, ETS-domain protein(SRF accessory protein 1)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu ELK4

Target: ELK4 (ELK4, ETS-Domain Protein (SRF Accessory Protein 1) (ELK4))

Andere Bezeichnung: ELK4

Hintergrund:

Synonyms: ETS domain-containing protein Elk-4|Serum response factor accessory protein 1 (SAP-1, SRF accessory protein 1)|ELK4|SAP1

Background: Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18'(H3K18Ac) and subsequent transcription repression. Forms a ternary complex with the serum response factor(SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously.

Molekulargewicht: 47 kDa

Gen-ID: 2005

UniProt: P28324