CD39 Antikörper

Produktnummer ABIN7113721

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CD39 in WB, FACS, IHC, ELISA und IP. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für CD39 Antikörper (ABIN7113721)

Target: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD39 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Produktdetails anti-CD39 Antikörper

Verwendungszweck: ENTPD1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: ectonucleoside triphosphate diphosphohydrolase 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu CD39

Target: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Andere Bezeichnung: ENTPD1

Hintergrund:

Synonyms: Ectonucleoside triphosphate diphosphohydrolase 1|ATP diphosphohydrolase (ATP-DPH, ATPDase)|Ecto-ATP diphosphohydrolase 1 (Ecto-ATPDase 1, Ecto-ATPase 1)|Ecto-apyrase|Lymphoid cell activation antigen|Nucleoside triphosphate diphosphohydrolase 1 (NTPDase1)|ENTPD1|CD39

Background: ENTPD1(Ectonucleoside triphosphate diphosphohydrolase 1) is also named as CD39, NTPDase 1, Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system, it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.It is a noncovalent tetrameric protein and that detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers(PMID: 9733785).And it is a 70-to 100- kDa protein that is heavily N-glycosylated(PMID:7930580). It has 3 isoforms produced by alternative splicing. CD39 preferentially occurred as a dimer that could be dissociated into monomeric forms.(PMID: 12694193). The soluble isoform of CD39(38-478 amino acid) locates to the extracellular part and FNab01474 recognizes both the 3 isoforms and soluble form of CD39(38-478aa) molecule.

Molekulargewicht: 75-95 kDa

UniProt: P49961