Der Kaninchen Polyklonal Anti-RAD18-Antikörper wurde für WB, ELISA, IHC und IF validiert. Er ist geeignet, RAD18 in Proben von Human, Ratte und Maus zu detektieren.
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
RAD18
(E3 ubiquitin-protein ligase RAD18 (RAD18))
Andere Bezeichnung
RAD18
Hintergrund
Synonyms:RNF73 Background:The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.