DDIT3 Antikörper
Kurzübersicht für DDIT3 Antikörper (ABIN7113561)
Target
Alle DDIT3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Aufreinigung
- Protein A+G purification
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- DNA-damage-inducible transcript 3
-
Isotyp
- IgG2a
-
-
-
-
Applikationshinweise
- WB: 1:500-1:5000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
-
Haltbarkeit
- 12 months
-
-
- DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
-
Andere Bezeichnung
- CHOP, GADD153
-
Hintergrund
- Synonyms:C/EBP homologous protein, C/EBP homologous protein 10, CEBPZ, CHOP, CHOP 10, CHOP, GADD153, CHOP10, DDIT 3, DDIT3, GADD153 Background:CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.
-
Molekulargewicht
- 30 kDa
-
UniProt
- P35638
-
Pathways
- Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
Target
-