Dieses Anti-Desmoglein 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Desmoglein 1 in WB, IHC, IF und ELISA. Geeignet für Human und Ratte.
Produktnummer ABIN7113447
Kurzübersicht für Desmoglein 1 Antikörper (ABIN7113447)
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
Desmoglein 1 (DSG1)
Andere Bezeichnung
DSG1
Hintergrund
Synonyms:DSG1, CDHF4, DG1, DSG Background:This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.