DCUN1D1 Antikörper
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- Target Alle DCUN1D1 Antikörper anzeigen
- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DCUN1D1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- DCN1, defective in cullin neddylation 1, domain containing 1(S. cerevisiae)
- Isotyp
- IgG
- Top Product
- Discover our top product DCUN1D1 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
- Andere Bezeichnung
- DCUN1D1 (DCUN1D1 Produkte)
- Synonyme
- fd19a01 antikoerper, zgc:66414 antikoerper, wu:fd19a01 antikoerper, dcun1l1 antikoerper, rp42 antikoerper, sccro antikoerper, scro antikoerper, tes3 antikoerper, DCNL1 antikoerper, DCUN1L1 antikoerper, RP42 antikoerper, SCCRO antikoerper, SCRO antikoerper, Tes3 antikoerper, Rp42 antikoerper, pTes3 antikoerper, DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) antikoerper, DCN1-like protein 1 antikoerper, DCN1, defective in cullin neddylation 1, domain containing 1 L homeolog antikoerper, defective in cullin neddylation 1 domain containing 1 antikoerper, dcun1d1 antikoerper, dcnl1 antikoerper, dcun1d1.L antikoerper, DCUN1D1 antikoerper, Dcun1d1 antikoerper
- Hintergrund
- Synonyms:DCUN1L1, RP42, SCCRO Background:Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8(UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates(PubMed:25349211). Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression(By similarity).
- Molekulargewicht
- 28 kDa
- Gen-ID
- 54165
- UniProt
- Q96GG9
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