DCUN1D1 Antikörper
Kurzübersicht für DCUN1D1 Antikörper (ABIN7113384)
Target
Alle DCUN1D1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- DCN1, defective in cullin neddylation 1, domain containing 1(S. cerevisiae)
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Isotyp
- IgG
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anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-89) antibody
DCUN1D1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 3D7 unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-89) antibodyDCUN1D1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4B5 unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) antibodyDCUN1D1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-89) antibodyDCUN1D1 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 31-80) antibodyDCUN1D1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Fledermaus, Huhn, Affe, Xenopus laevis, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) antibodyDCUN1D1 Reaktivität: Human, Maus, Ratte, Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (N-Term) antibodyDCUN1D1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) antibodyDCUN1D1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 15-70) antibodyDCUN1D1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (C-Term) antibodyVerified DCUN1D1 Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
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Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
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Andere Bezeichnung
- DCUN1D1
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Hintergrund
- Synonyms:DCUN1L1, RP42, SCCRO Background:Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8(UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates(PubMed:25349211). Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression(By similarity).
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Molekulargewicht
- 28 kDa
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Gen-ID
- 54165
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UniProt
- Q96GG9
Target
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