Non-Syndromic Hearing Impairment Protein 5 (GSDME) (AA 1-152) Antikörper
Kurzübersicht für Non-Syndromic Hearing Impairment Protein 5 (GSDME) (AA 1-152) Antikörper (ABIN7113358)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-152
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Verwendungszweck
- GSDME antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 1-152aa
Immunogen: deafness, autosomal dominant 5
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- Non-Syndromic Hearing Impairment Protein 5 (GSDME)
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Andere Bezeichnung
- GSDME
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Hintergrund
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Synonyms: Gasdermin-E|Inversely correlated with estrogen receptor expression 1 (ICERE-1)|Non-syndromic hearing impairment protein 5|Gasdermin-E, N-terminal (GSDME-NT)|Gasdermin-E, C-terminal (GSDME-CT)|GSDME|DFNA5|ICERE1
Background: Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.
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Molekulargewicht
- 54 kDa
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Gen-ID
- 1687
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UniProt
- O60443
Target
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