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DACH2 Antikörper

DACH2 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7113311
  • Target Alle DACH2 Antikörper anzeigen
    DACH2 (Dachshund 2 (DACH2))
    Reaktivität
    • 34
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 34
    • 1
    • 1
    Kaninchen
    Klonalität
    • 36
    Polyklonal
    Konjugat
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DACH2 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 17
    • 13
    • 13
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    dachshund homolog 2(Drosophila)
    Isotyp
    IgG
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  • Applikationshinweise
    WB: 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    DACH2 (Dachshund 2 (DACH2))
    Andere Bezeichnung
    DACH2 (DACH2 Produkte)
    Synonyme
    9430028N04Rik antikoerper, RGD1561687 antikoerper, dachshund family transcription factor 2 antikoerper, dachshund 2 (Drosophila) antikoerper, dachshund family transcription factor 2 L homeolog antikoerper, dachshund homolog 2 antikoerper, dachshund homolog 2 (Drosophila) antikoerper, DACH2 antikoerper, Dach2 antikoerper, dach2.L antikoerper, LOC612847 antikoerper, dach2 antikoerper
    Hintergrund
    Synonyms: Background:Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression(By similarity). Probably binds to DNA via its DACHbox-N domain.
    Molekulargewicht
    65 kDa
    Gen-ID
    117154
    UniProt
    Q96NX9
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