COPE Antikörper

Produktnummer ABIN7112910

Dieses Anti-COPE-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von COPE in WB, ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für COPE Antikörper (ABIN7112910)

Target: COPE (Coatomer Protein Complex, Subunit epsilon (COPE))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-COPE Antikörper

Verwendungszweck: COPE antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: coatomer protein complex, subunit epsilon

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu COPE

Target: COPE (Coatomer Protein Complex, Subunit epsilon (COPE))

Andere Bezeichnung: COPE

Hintergrund:

Synonyms: Coatomer subunit epsilon|Epsilon-coat protein (Epsilon-COP)|COPE

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors(ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors(By similarity).

Molekulargewicht: 36 kDa

Gen-ID: 11316

UniProt: O14579