CXCR4 Antikörper (AA 200-352)

Produktnummer ABIN7112680

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CXCR4 in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für CXCR4 Antikörper (AA 200-352) (ABIN7112680)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CXCR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Klon: 9H1

Produktdetails anti-CXCR4 Antikörper

Bindungsspezifität: AA 200-352

Verwendungszweck: CXCR4 antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 200-352aa

Immunogen: chemokine(C-X-C motif) receptor 4

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Andere Bezeichnung: CXCR4

Hintergrund:

Synonyms: C-X-C chemokine receptor type 4 (CXC-R4, CXCR-4)|FB22|Fusin|HM89|LCR1|Leukocyte-derived seven transmembrane domain receptor (LESTR)|Lipopolysaccharide-associated protein 3 (LAP-3, LPS-associated protein 3)|NPYRL|Stromal cell-derived factor 1 receptor (SDF-1 receptor)|CXCR4

Background: The chemokine receptor CXCR4, a 7-transmembrane protein on cell surface, acts with the CD4 protein to support HIV entry into cells. CXCR4 is highly expressed in brain and heart, white blood cells, vascular endothelial cells, and umbilical cord endothelial cells. Several CXCR4 isoforms have been identified with molecular weights of 47, 50, 62 and 98 kDa. The 62-64 kDa CXCR4 is predominantly ubiquitinated and is preferentially associated with CD4. This antibody recognizes the 62kd CXCR4.

Molekulargewicht: 60-70 kDa

Gen-ID: 7852

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events