CRCP Antikörper

Produktnummer ABIN7112634

Dieses Anti-CRCP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CRCP in ELISA, WB, IHC, IP und FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für CRCP Antikörper (ABIN7112634)

Target: CRCP (CGRP Receptor Component (CRCP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRCP Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)

Produktdetails anti-CRCP Antikörper

Verwendungszweck: CRCP antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: CGRP receptor component

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:4000, IP: 1:500-1:2000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu CRCP

Target: CRCP (CGRP Receptor Component (CRCP))

Andere Bezeichnung: CRCP

Hintergrund:

Synonyms: DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9)|Calcitonin gene-related peptide-receptor component protein (CGRP-RCP, CGRP-receptor component protein, CGRPRCP, HsC17)|CRCP

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).

Molekulargewicht: 20 kDa

Gen-ID: 27297

UniProt: O75575