CIDEA Antikörper

Produktnummer ABIN7112559

Dieses Anti-CIDEA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CIDEA in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für CIDEA Antikörper (ABIN7112559)

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIDEA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CIDEA Antikörper

Verwendungszweck: CIDEA antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: cell death-inducing DFFA-like effector a

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu CIDEA

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Andere Bezeichnung: CIDEA

Hintergrund:

Synonyms: Lipid transferase CIDEA|Cell death activator CIDE-A|Cell death-inducing DFFA-like effector A|CIDEA

Background: Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter(By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.

Molekulargewicht: 25 kDa

Gen-ID: 1149

UniProt: O60543