CD8 alpha Antikörper
Kurzübersicht für CD8 alpha Antikörper (ABIN7112526)
Target
Alle CD8 alpha (CD8A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Aufreinigung
- Immunogen affinity purified
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- CD8A
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
-
Haltbarkeit
- 12 months
-
-
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
-
Andere Bezeichnung
- CD8A
-
Hintergrund
- Synonyms:CD8, Leu2, MAL, p32 Background:The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
-
Molekulargewicht
- 30 kDa
-
Gen-ID
- 925
-
UniProt
- P01732
-
Pathways
- T-Zell Rezeptor Signalweg
Target
-