CD320 Antikörper (AA 80-282)
Kurzübersicht für CD320 Antikörper (AA 80-282) (ABIN7112479)
Target
Alle CD320 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 80-282
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Verwendungszweck
- CD320 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 80-282aa
Immunogen: CD320 molecule
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:1000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- CD320 (CD320 Molecule (CD320))
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Andere Bezeichnung
- CD320
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Hintergrund
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Synonyms: CD320 antigen|8D6 antigen|FDC-signaling molecule 8D6 (FDC-SM-8D6)|Transcobalamin receptor (TCblR)|CD320|8D6A
Background: CD320, also known as 8D6, 8D6A or TCblR, is a single-pass type I membrane protein containing 2 LDL-receptor class A domains. Expressed abundantly on follicular dendritic cells (FDCs), CD320 has been shown to enhance proliferation of germinal center (GC) B cells. It is the receptor for cellular uptake of transcobalamin-bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC). CD320 has a calculated molecular mass of 29 kDa. This antibody detects bands at 50-55 kDa and 60-70 kDa, probably caused by extensive complex glycosylation.
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Molekulargewicht
- 50-55 kDa, 60-70 kDa
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Gen-ID
- 51293
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UniProt
- Q9NPF0
Target
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