CD2AP Antikörper
Kurzübersicht für CD2AP Antikörper (ABIN7112459)
Target
Alle CD2AP (Cd2ap) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- CD2AP antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- CD2-associated protein
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:500-1:1000, IF: 1:10-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
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Andere Bezeichnung
- CD2AP
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Hintergrund
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Synonyms: CD2-associated protein|Adapter protein CMS|Cas ligand with multiple SH3 domains|CD2AP
Background: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.
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Molekulargewicht
- 70 kDa
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Gen-ID
- 23607
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UniProt
- Q9Y5K6
Target
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