CNOT7 Antikörper
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- Target Alle CNOT7 Antikörper anzeigen
- CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CNOT7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- CCR4-NOT transcription complex, subunit 7
- Isotyp
- IgG
- Top Product
- Discover our top product CNOT7 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))
- Andere Bezeichnung
- CNOT7 (CNOT7 Produkte)
- Hintergrund
- Synonyms:CAF1 Background:Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
- Molekulargewicht
- 33-35 kDa
- Gen-ID
- 29883
- UniProt
- Q9UIV1
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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