CTCFL Antikörper (AA 361-663)

Produktnummer ABIN7112427

Dieses Anti-CTCFL-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CTCFL in WB, ELISA und IF. Geeignet für Human und Maus.

Kurzübersicht für CTCFL Antikörper (AA 361-663) (ABIN7112427)

Target: CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTCFL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Klon: 2B10

Produktdetails anti-CTCFL Antikörper

Bindungsspezifität: AA 361-663

Verwendungszweck: CTCFL antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 361-663aa

Immunogen: CCCTC-binding factor(zinc finger protein)-like

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IF: 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu CTCFL

Target: CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

Andere Bezeichnung: CTCFL

Hintergrund:

Synonyms: Transcriptional repressor CTCFL|Brother of the regulator of imprinted sites|CCCTC-binding factor|CTCF paralog|CTCF-like protein|Cancer/testis antigen 27 (CT27)|Zinc finger protein CTCF-T|CTCFL|BORIS

Background: CTCFL, also named BORIS(for brother of the regulator of imprinted sites) is a paralogue of the 11 zinc-finger transcription factor, CTCF. It is predominantly expressed in spermatocytes in the testis, also can be found in tumors and cancer cell lines. It mainly participates in insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. It has a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region(ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2.

Molekulargewicht: 75 kDa

Gen-ID: 140690

UniProt: Q8NI51