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BEX2 Antikörper

BEX2 Reaktivität: Human, Maus, Ratte ELISA, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7112040
  • Target Alle BEX2 Antikörper anzeigen
    BEX2 (Brain Expressed X-Linked 2 (BEX2))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 14
    Kaninchen
    Klonalität
    • 14
    Polyklonal
    Konjugat
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BEX2 Antikörper ist unkonjugiert
    Applikation
    • 6
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    brain expressed X-linked 2
    Isotyp
    IgG
    Top Product
    Discover our top product BEX2 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:1000, IHC: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    BEX2 (Brain Expressed X-Linked 2 (BEX2))
    Andere Bezeichnung
    BEX2 (BEX2 Produkte)
    Synonyme
    BEX1 antikoerper, DJ79P11.1 antikoerper, AL024066 antikoerper, Bex1 antikoerper, EG2RVC antikoerper, brain expressed X-linked 2 antikoerper, BEX2 antikoerper, Bex2 antikoerper
    Hintergrund
    Synonyms:BEX1, BEX1/2, BEX2, brain expressed X linked 2, hBex2, Protein BEX2 Background:Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94 % . This antibody detects both BEX1 and BEX2.
    Molekulargewicht
    10-15 kDa
    Gen-ID
    84707
    UniProt
    Q9BXY8
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