BEX2 Antikörper

Produktnummer ABIN7112040

Dieses Anti-BEX2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BEX2 in ELISA, IHC und WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für BEX2 Antikörper (ABIN7112040)

Target: BEX2 (Brain Expressed X-Linked 2 (BEX2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BEX2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-BEX2 Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: brain expressed X-linked 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu BEX2

Target: BEX2 (Brain Expressed X-Linked 2 (BEX2))

Andere Bezeichnung: BEX2

Hintergrund: Synonyms:BEX1, BEX1/2, BEX2, brain expressed X linked 2, hBex2, Protein BEX2 Background:Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94 % . This antibody detects both BEX1 and BEX2.

Molekulargewicht: 10-15 kDa

Gen-ID: 84707

UniProt: Q9BXY8