ATP5F1C (AA 1-298) Antikörper

Produktnummer ABIN7111799

Der Maus Monoklonal Anti--Antikörper wurde für ELISA, WB und IHC validiert. Er ist geeignet, in Proben von Human zu detektieren.

Kurzübersicht für ATP5F1C (AA 1-298) Antikörper (ABIN7111799)

Target: ATP5F1C

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Klon: 8H11

Produktdetails

Bindungsspezifität: AA 1-298

Verwendungszweck: ATP5F1C antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-298aa

Immunogen: ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Antigendetails

Target: ATP5F1C

Hintergrund:

Synonyms: ATP synthase subunit gamma, mitochondrial|ATP synthase F1 subunit gamma|F-ATPase gamma subunit|ATP5F1C|ATP5C|ATP5C1|ATP5CL1

Background: Mitochondrial membrane ATP synthase(F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1)-containing the extramembraneous catalytic core, and F(0)-containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

Molekulargewicht: 33 kDa

Gen-ID: 509

UniProt: P36542