Aryl Hydrocarbon Receptor Antikörper

Produktnummer ABIN7111734

Dieses Anti-Aryl Hydrocarbon Receptor-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Aryl Hydrocarbon Receptor in WB, IHC, ELISA und IP. Geeignet für Human und Maus.

Kurzübersicht für Aryl Hydrocarbon Receptor Antikörper (ABIN7111734)

Target: Aryl Hydrocarbon Receptor (AHR)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aryl Hydrocarbon Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Produktdetails anti-Aryl Hydrocarbon Receptor Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: aryl hydrocarbon receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Andere Bezeichnung: AHR

Hintergrund: Synonyms:Ah receptor, AHR, aryl hydrocarbon receptor, bHLHe76 Background:Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.

Molekulargewicht: 105 kDa

Gen-ID: 196

UniProt: P35869

Pathways: Regulation of Cell Size