Aryl Hydrocarbon Receptor Antikörper (AA 12-215)
Kurzübersicht für Aryl Hydrocarbon Receptor Antikörper (AA 12-215) (ABIN7111734)
Target
Alle Aryl Hydrocarbon Receptor (AHR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 12-215
-
Verwendungszweck
- AHR antibody
-
Aufreinigung
- Immunogen affinity purified
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
-
Immunogen sequence: 12-215aa
Immunogen: aryl hydrocarbon receptor
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze / thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months
-
Haltbarkeit
- 12 months
-
-
- Aryl Hydrocarbon Receptor (AHR)
-
Andere Bezeichnung
- AHR
-
Hintergrund
-
Synonyms: Aryl hydrocarbon receptor (Ah receptor, AhR)|Class E basic helix-loop-helix protein 76 (bHLHe76)|AHR|BHLHE76
Background: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
-
Molekulargewicht
- 105 kDa
-
Gen-ID
- 196
-
UniProt
- P35869
-
Pathways
- Regulation of Cell Size
Target
-