AKR1C2 Antikörper

Produktnummer ABIN7111467

Dieser Anti-AKR1C2-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von AKR1C2 in WB, ELISA und IF. Geeignet für Human, Ratte und Maus.

Kurzübersicht für AKR1C2 Antikörper (ABIN7111467)

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-AKR1C2 Antikörper

Verwendungszweck: AKR1C2 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: Aldo-keto reductase family 1 member C2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IF: 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu AKR1C2

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Andere Bezeichnung: AKR1C2

Hintergrund:

Synonyms: Aldo-keto reductase family 1 member C2|3-alpha-HSD3|Chlordecone reductase homolog HAKRD|Dihydrodiol dehydrogenase 2 (DD-2, DD2)|Dihydrodiol dehydrogenase/bile acid-binding protein (DD/BABP)|Type III 3-alpha-hydroxysteroid dehydrogenase|AKR1C2|DDH2

Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.

Molekulargewicht: 37 kDa

UniProt: P52895

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process