AKR1C4 Antikörper

Produktnummer ABIN7111464

Dieses Anti-AKR1C4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von AKR1C4 in WB, ELISA und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für AKR1C4 Antikörper (ABIN7111464)

Target: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-AKR1C4 Antikörper

Verwendungszweck: AKR1C4 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: aldo-keto reductase family 1, member C4(chlordecone reductase, 3-alpha hydroxysteroid dehydrogenase, type I, dihydrodiol dehydrogenase 4)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:10000, IF: 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu AKR1C4

Target: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Andere Bezeichnung: AKR1C4

Hintergrund:

Synonyms: Aldo-keto reductase family 1 member C4|3-alpha-hydroxysteroid dehydrogenase type I (3-alpha-HSD1)|3alpha-hydroxysteroid 3-dehydrogenase|Chlordecone reductase (CDR)|Dihydrodiol dehydrogenase 4 (DD-4, DD4)|HAKRA|AKR1C4|CHDR

Background: Catalyzes the transformation of the potent androgen dihydrotestosterone(DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol(3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone(kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.

Molekulargewicht: 37 kDa

Gen-ID: 1109

UniProt: P17516

Pathways: Steroid Hormone Biosynthesis