Alanine--tRNA Ligase, Mitochondrial (AARS-1) Antikörper

Produktnummer ABIN7111429

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in ELISA, IF, WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Alanine--tRNA Ligase, Mitochondrial (AARS-1) Antikörper (ABIN7111429)

Target: Alanine--tRNA Ligase, Mitochondrial (AARS-1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails

Verwendungszweck: AARS1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: alanyl-tRNA synthetase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Antigendetails

Target: Alanine--tRNA Ligase, Mitochondrial (AARS-1)

Andere Bezeichnung: AARS1

Hintergrund:

Synonyms: Alanine--tRNA ligase, cytoplasmic|Alanyl-tRNA synthetase (AlaRS)|Renal carcinoma antigen NY-REN-42|AARS1|AARS

Background: AARS(alanyl-tRNA synthetase) is also named as AlaRS(alanine tRNA ligase 1, cytoplasmic), renal carcinoma antigen NY-REN-42 and belongs to the class-II aminoacyl-tRNA synthetase family. It can interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. AARS consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs(PMID:19661429).

Molekulargewicht: 107 kDa

Gen-ID: 16

UniProt: P49588