ARL2 Antikörper

Produktnummer ABIN7111380

Dieses Anti-ARL2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ARL2 in WB, ELISA und IHC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für ARL2 Antikörper (ABIN7111380)

Target: ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-ARL2 Antikörper

Verwendungszweck: ARL2 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: ADP-ribosylation factor-like 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu ARL2

Target: ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))

Andere Bezeichnung: ARL2

Hintergrund:

Synonyms: ADP-ribosylation factor-like protein 2|ARL2

Background: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle.

Molekulargewicht: 21-25 kDa

Gen-ID: 402

UniProt: P36404

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location