ADIPOQ Antikörper (AA 1-244)

Produktnummer ABIN7111358

Der Maus Monoklonal Anti-ADIPOQ-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, ADIPOQ in Proben von Human und Maus zu detektieren.

Kurzübersicht für ADIPOQ Antikörper (AA 1-244) (ABIN7111358)

Target: ADIPOQ (Adiponectin (ADIPOQ))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ADIPOQ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 6E1

Produktdetails anti-ADIPOQ Antikörper

Bindungsspezifität: AA 1-244

Verwendungszweck: ADIPOQ antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-244aa

Immunogen: adiponectin, C1Q and collagen domain containing

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu ADIPOQ

Target: ADIPOQ (Adiponectin (ADIPOQ))

Andere Bezeichnung: ADIPOQ

Hintergrund:

Synonyms: Adiponectin|30 kDa adipocyte complement-related protein|Adipocyte complement-related 30 kDa protein (ACRP30)|Adipocyte, C1q and collagen domain-containing protein|Adipose most abundant gene transcript 1 protein (apM-1)|Gelatin-binding protein|ADIPOQ|ACDC|ACRP30|APM1|GBP28

Background: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Molekulargewicht: 26 kDa

Gen-ID: 9370

UniProt: Q15848