ADCY6 Antikörper

Produktnummer ABIN7111340

Der Kaninchen Polyklonal Anti-ADCY6-Antikörper wurde für WB, ELISA und IP validiert. Er ist geeignet, ADCY6 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ADCY6 Antikörper (ABIN7111340)

Target: ADCY6 (Adenylate Cyclase 6 (ADCY6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADCY6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Produktdetails anti-ADCY6 Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: adenylate cyclase 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200-1:2000, IP: 1:200-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ADCY6

Target: ADCY6 (Adenylate Cyclase 6 (ADCY6))

Andere Bezeichnung: ADCY6

Hintergrund: Synonyms:AC6, ADCY6, adenylate cyclase 6, Adenylate cyclase type 6, Adenylate cyclase type VI, Adenylyl cyclase 6, ATP pyrophosphate lyase 6, DKFZp779F075, KIAA0422 Background:Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors(PubMed:17916776, PubMed:17110384). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells(PubMed:17916776). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion(By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA. This promotes increased phosphorylation of various proteins, including AKT. Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility. May contribute to normal heart function(By similarity). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol(PubMed:17916776). Contributes to bone cell responses to mechanical stimuli(By similarity).

Molekulargewicht: 131 kDa

Gen-ID: 112

UniProt: O43306

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma