ACOT7
Reaktivität: Human
IHC, FACS, ICC, IF
Wirt: Kaninchen
Polyclonal
PE
Applikationshinweise
WB: 1:1000-1:5000, IHC: 1:20-1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Jakopovic, Horvatić, Baranasic, Car, Oršolić, Jakopovich, Sedić, Kraljević Pavelić: "Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pathways." in: Frontiers in pharmacology, Vol. 15, pp. 1475102, (2024) (PubMed).
Synonyms:ACOT7, LACH1, LACH, acyl CoA thioesterase 7, ACH1 Background:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A(CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in brain. May play a regulatory role by modulating the cellular levels of fatty acyl-CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA.