ACOX1 Antikörper (AA 1-270)

Produktnummer ABIN7111266

Dieser Anti-ACOX1-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von ACOX1 in WB, IHC, ELISA und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für ACOX1 Antikörper (AA 1-270) (ABIN7111266)

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACOX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-ACOX1 Antikörper

Bindungsspezifität: AA 1-270

Verwendungszweck: ACOX1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-270aa

Immunogen: acyl-Coenzyme A oxidase 1, palmitoyl

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000, IHC: 1:100 - 1:200, IF: 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu ACOX1

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Andere Bezeichnung: ACOX1

Hintergrund:

Synonyms: Peroxisomal acyl-coenzyme A oxidase 1 (AOX)|Palmitoyl-CoA oxidase|Peroxisomal fatty acyl-CoA oxidase|Straight-chain acyl-CoA oxidase (SCOX)|Peroxisomal acyl-CoA oxidase 1, A chain|Peroxisomal acyl-CoA oxidase 1, B chain|Peroxisomal acyl-CoA oxidase 1, C chain|ACOX1|ACOX

Background: The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.It has 3 isoforms produced by alternative splicing with the molecular mass of 70-74 kDa and can be cleaved post-translationally into a 50- kDa and a 22- kDa subunit between Val468 and Ala469 (PMID: 10672038).

Molekulargewicht: 74 kDa

Gen-ID: 51

UniProt: Q15067

Pathways: Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process