alpha Actinin 4 Antikörper (AA 720-911)

Produktnummer ABIN7111233

Dieses Anti-alpha Actinin 4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von alpha Actinin 4 in WB, ELISA, IHC, IP, IF und FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für alpha Actinin 4 Antikörper (AA 720-911) (ABIN7111233)

Target: alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha Actinin 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-alpha Actinin 4 Antikörper

Bindungsspezifität: AA 720-911

Verwendungszweck: ACTN4 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 720-911aa

Immunogen: actinin, alpha 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:500-1:5000, IF: 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu alpha Actinin 4

Target: alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Andere Bezeichnung: ACTN4

Hintergrund:

Synonyms: Alpha-actinin-4|Non-muscle alpha-actinin 4|ACTN4

Background: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein(Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation(PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions(By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA(PubMed:22351778).

Molekulargewicht: 105 kDa

Gen-ID: 81

UniProt: O43707

Pathways: Proton Transport