ACPP Antikörper (AA 27-373)
Kurzübersicht für ACPP Antikörper (AA 27-373) (ABIN7111188)
Target
Alle ACPP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 27-373
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Verwendungszweck
- ACP3 antibody
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Aufreinigung
- Protein A+G purification
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 27-373aa
Immunogen: acid phosphatase, prostate
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Isotyp
- IgG2a
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Applikationshinweise
- WB: 1:200-1:2000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- ACPP (Acid Phosphatase, Prostate (ACPP))
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Andere Bezeichnung
- ACP3
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Hintergrund
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Synonyms: Prostatic acid phosphatase (PAP)|5'-nucleotidase (5'-NT)|Acid phosphatase 3|Ecto-5'-nucleotidase|Protein tyrosine phosphatase ACP3|Thiamine monophosphatase (TMPase)|PAPf39|ACP3|ACPP
Background: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions( pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion(DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.
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Molekulargewicht
- 48 kDa
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Gen-ID
- 55
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UniProt
- P15309
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Pathways
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
Target
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