ABHD2 Antikörper
Kurzübersicht für ABHD2 Antikörper (ABIN7111166)
Target
Alle ABHD2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- ABHD2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- abhydrolase domain containing 2
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:5000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))
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Andere Bezeichnung
- ABHD2
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Hintergrund
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Synonyms: Monoacylglycerol lipase ABHD2|2-arachidonoylglycerol hydrolase|Abhydrolase domain-containing protein 2|Acetylesterase|Lung alpha/beta hydrolase 2|Progesterone-sensitive lipase|Protein PHPS1-2|ABHD2|LABH2
Background: Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol(AG) from cell membrane(PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol(1AG) and 2-arachidonoylglycerol(2AG) to glycerol and arachidonic acid(AA)(PubMed:26989199). Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation(PubMed:26989199). May also play a role in smooth muscle cells migration(By similarity).
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Molekulargewicht
- 48 kDa
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Gen-ID
- 11057
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UniProt
- P08910
Target
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