XRN1 Antikörper (AA 200-450)
Kurzübersicht für XRN1 Antikörper (AA 200-450) (ABIN7111134)
Target
Alle XRN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 200-450
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Verwendungszweck
- XRN1 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 200-450aa
Immunogen: 5'-3' exoribonuclease 1
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- XRN1 (5'-3' Exoribonuclease 1 (XRN1))
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Andere Bezeichnung
- XRN1
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Hintergrund
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Synonyms: 5'-3' exoribonuclease 1|Strand-exchange protein 1 homolog|XRN1|45536
Background: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA(By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma(OGS).
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Molekulargewicht
- 192 kDa
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Gen-ID
- 54464
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UniProt
- Q8IZH2
Target
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