CXCL13 Antikörper (AA 23-109)

Produktnummer ABIN706691

Der Kaninchen Polyklonal Anti-CXCL13-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, CXCL13 in Proben von Maus und Ratte zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für CXCL13 Antikörper (AA 23-109) (ABIN706691)

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCL13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CXCL13 Antikörper

Bindungsspezifität: AA 23-109

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CXCL13/BCA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CXCL13 Antikörper (ABIN706691)

Doloff, Veiseh, Vegas, Tam, Farah, Ma, Li, Bader, Chiu, Sadraei, Aresta-Dasilva, Griffin, Jhunjhunwala, Webber, Siebert, Tang, Chen, Langan, Dholokia, Thakrar, Qi, Oberholzer, Greiner, Langer et al.: "Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates. ..." in: Nature materials, Vol. 16, Issue 6, pp. 671-680, (2017) (PubMed).

Wang, Cao, Li, Zhang: "Chemokine CXCL13 expression was up-regulated in Clostridium difficile infection." in: Cytokine, Vol. 88, pp. 232-240, (2016) (PubMed).

Siepert, Brösel, Vogt, Ahrlich, Schmitt-Knosalla, Loddenkemper, Kühl, Baumgrass, Gerstmayer, Tomiuk, Tiedge, Viklický, Brabcova, Nizze, Lehmann, Volk, Sawitzki: "Mechanisms and Rescue Strategies of Calcineurin Inhibitor Mediated Tolerance Abrogation Induced by Anti-CD4 mAb Treatment." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, (2013) (PubMed).

Details zu CXCL13

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Andere Bezeichnung: CXCL13/BCA1

Hintergrund:

Synonyms: BLC, Angie, BCA-1, BLR1L, ANGIE2, Scyb13, 4631412M8Rik, C-X-C motif chemokine 13, B lymphocyte chemoattractant, CXC chemokine BLC, Small-inducible cytokine B13, Cxcl13

Background: Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs.

Gen-ID: 55985

UniProt: O55038