CXCL13 Antikörper (AA 23-109)

Produktnummer ABIN706691

Es sind 3+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-CXCL13 Antikörper wird verwendet zum Nachweis von CXCL13 in Proben von Maus und Ratte. Er wurde validiert für WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro).

Kurzübersicht für CXCL13 Antikörper (AA 23-109) (ABIN706691)

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCL13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CXCL13 Antikörper

Bindungsspezifität: AA 23-109

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CXCL13/BCA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CXCL13 Antikörper (ABIN706691)

Doloff, Veiseh, Vegas, Tam, Farah, Ma, Li, Bader, Chiu, Sadraei, Aresta-Dasilva, Griffin, Jhunjhunwala, Webber, Siebert, Tang, Chen, Langan, Dholokia, Thakrar, Qi, Oberholzer, Greiner, Langer et al.: "Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates. ..." in: Nature materials, Vol. 16, Issue 6, pp. 671-680, (2017) (PubMed).

Wang, Cao, Li, Zhang: "Chemokine CXCL13 expression was up-regulated in Clostridium difficile infection." in: Cytokine, Vol. 88, pp. 232-240, (2016) (PubMed).

Siepert, Brösel, Vogt, Ahrlich, Schmitt-Knosalla, Loddenkemper, Kühl, Baumgrass, Gerstmayer, Tomiuk, Tiedge, Viklický, Brabcova, Nizze, Lehmann, Volk, Sawitzki: "Mechanisms and Rescue Strategies of Calcineurin Inhibitor Mediated Tolerance Abrogation Induced by Anti-CD4 mAb Treatment." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, (2013) (PubMed).

Details zu CXCL13

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Andere Bezeichnung: CXCL13/BCA1

Hintergrund:

Synonyms: BLC, Angie, BCA-1, BLR1L, ANGIE2, Scyb13, 4631412M8Rik, C-X-C motif chemokine 13, B lymphocyte chemoattractant, CXC chemokine BLC, Small-inducible cytokine B13, Cxcl13

Background: Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs.

Gen-ID: 55985

UniProt: O55038