VTA1 Antikörper (AA 221-306)

Produktnummer ABIN7091817

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VTA1 in IHC (p). Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für VTA1 Antikörper (AA 221-306) (ABIN7091817)

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VTA1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-VTA1 Antikörper

Bindungsspezifität: AA 221-306

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Sheep,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LIP5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu VTA1

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Andere Bezeichnung: LIP5

Hintergrund:

Synonyms: C6orf55 Chromosome 6 open reading frame 55, Dopamine responsive protein DRG 1, Dopamine-responsive gene 1 protein, DRG 1, DRG-1, DRG1, Homolog of mouse SKD1 binding protein 1, HSPC228, LIP5, LYST interacting protein 5, LYST-interacting protein 5, My012, SBP1, SKD1 binding protein 1, SKD1-binding protein 1, Vacuolar protein sorting-associated protein VTA1 homolog, Vps20 associated 1 homolog (S. cerevisiae), VTA1, VTA1_HUMAN

Background: Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR. Involved in HIV-1 budding.

Gen-ID: 51534

UniProt: Q9NP79