UCHL1 Antikörper (AA 151-223)

Produktnummer ABIN7091799

Dieser Maus Monoklonal Antikörper detektiert spezifisch UCHL1 in WB, IF, IHC (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für UCHL1 Antikörper (AA 151-223) (ABIN7091799)

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser UCHL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: T2F5

Produktdetails anti-UCHL1 Antikörper

Bindungsspezifität: AA 151-223

Verwendungszweck: UCHL1/PGP9.5 Monoclonal Antibody

Kreuzreaktivität: Xenopus laevis

Homologie: Human,Mouse,Rat,Cow,Pig,Monkey

Aufreinigung: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human UCHL1/PGP9.5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB(WB=1:500-1000), IHC-P(IHC-P=1:20-50), IHC-F(IHC-F=1:400-800), IF(IF=1:100-500)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu UCHL1

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Andere Bezeichnung: UCHL1/PGP9.5

Hintergrund:

Synonyms: Gracile axonal dystrophy, Neuron cytoplasmic protein 9.5, Park 5, Park5, Parkinson Disease 5, PGP 9.5, PGP95, Protein gene product 9.5, Ubiquitin C terminal esterase L1, Ubiquitin C terminal hydrolase (neuron specific), Ubiquitin C terminal hydrolase, Ubiquitin carboxyl terminal esterase L1, Ubiquitin carboxyl terminal hydrolase isozyme L1, Ubiquitin carboxyl-terminal hydrolase isozyme L1, Ubiquitin thioesterase L1, Ubiquitin thiolesterase, Ubiquitin thiolesterase L1, UCH L1, UCH-L1, UCHL1, UCHL1_HUMAN.

Background: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.

Gen-ID: 7345

UniProt: P09936

Pathways: Feeding Behaviour