RAB23 Antikörper

Produktnummer ABIN7091627

Dieses Anti-RAB23-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von RAB23 in WB, ELISA und IF. Geeignet für Human.

Kurzübersicht für RAB23 Antikörper (ABIN7091627)

Target: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RAB23 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Klon: G6S4

Produktdetails anti-RAB23 Antikörper

Homologie: Human,Mouse

Immunogen: Recombinant human RAB23 (Fragment) (His-tagged).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IF()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RAB23

Target: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Andere Bezeichnung: RAB23

Hintergrund:

Synonyms: DKFZp781H0695, HSPC137, MGC8900, Rab 23, RAB family small GTP binding protein RAB 23, RAB23, member RAS oncogene family, RAB23_HUMAN, Ras related protein Rab 23, Ras-related protein Rab-23.

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.

Gen-ID: 51715

UniProt: Q9ULC3

Pathways: Tube Formation