Neuroligin 1 Antikörper (AA 621-720) (HRP)
Kurzübersicht für Neuroligin 1 Antikörper (AA 621-720) (HRP) (ABIN7091460)
Target
Alle Neuroligin 1 (NLGN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 621-720
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Kreuzreaktivität
- Human, Maus
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Homologie
- Dog,Cow,Sheep,Pig,Horse,Chicken
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Neuroligin 1
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Isotyp
- IgG
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Applikationshinweise
- WB 1:300-5000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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- Neuroligin 1 (NLGN1)
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Andere Bezeichnung
- Neuroligin 1
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Hintergrund
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Synonyms: NLG 1, KIAA1070, MGC45115, NLG1, Neuroligin-1, NLGN1, NLGN1_HUMAN.
Background: Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Subunit : Interacts with NRXN1, NRXN2 and NRXN3. Interacts with NLGN3. Interacts with AIP1 and PDZRN3. Interacts (via its C-terminus) with DLG4/PSD-95 (via PDZ domain 3). Interacts with GOPC.
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Gen-ID
- 22871
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UniProt
- Q8N2Q7
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Pathways
- Synaptic Membrane, Synaptic Vesicle Exocytosis
Target
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