MCMBP Antikörper (AA 551-642) (HRP)

Produktnummer ABIN7091415

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MCMBP in IHC (p). Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für MCMBP Antikörper (AA 551-642) (HRP) (ABIN7091415)

Target: MCMBP (Minichromosome Maintenance Complex Binding Protein (MCMBP))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCMBP Antikörper ist konjugiert mit HRP

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MCMBP Antikörper (HRP)

Bindungsspezifität: AA 551-642

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MCM-BP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Details zu MCMBP

Target: MCMBP (Minichromosome Maintenance Complex Binding Protein (MCMBP))

Andere Bezeichnung: MCM-BP

Hintergrund:

Synonyms: C10orf119 , chromosome 10 open reading frame 119 , MCM-binding protein , MCM-BP , mcmbp , MCMBP_HUMAN , Mini-chromosome maintenance complex-binding protein , Minichromosome maintenance complex binding protein.

Background: Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP, probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion.

Gen-ID: 79892

UniProt: Q9BTE3

Pathways: Chromatin Binding