MCMBP Antikörper (AA 551-642)

Produktnummer ABIN7091414

Dieser Anti-MCMBP-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von MCMBP in IHC (p). Geeignet für Ratte.

Kurzübersicht für MCMBP Antikörper (AA 551-642) (ABIN7091414)

Target: MCMBP (Minichromosome Maintenance Complex Binding Protein (MCMBP))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCMBP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MCMBP Antikörper

Bindungsspezifität: AA 551-642

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MCM-BP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu MCMBP

Target: MCMBP (Minichromosome Maintenance Complex Binding Protein (MCMBP))

Andere Bezeichnung: MCM-BP

Hintergrund:

Synonyms: C10orf119 , chromosome 10 open reading frame 119 , MCM-binding protein , MCM-BP , mcmbp , MCMBP_HUMAN , Mini-chromosome maintenance complex-binding protein , Minichromosome maintenance complex binding protein.

Background: Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP, probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion.

Gen-ID: 79892

UniProt: Q9BTE3

Pathways: Chromatin Binding