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MBD2 Antikörper (AA 10-228)

MBD2 Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal G7R2 unconjugated
Produktnummer ABIN7091410
  • Target Alle MBD2 Antikörper anzeigen
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-228
    Reaktivität
    • 47
    • 23
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 45
    • 1
    • 1
    Maus
    Klonalität
    • 45
    • 2
    Monoklonal
    Konjugat
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MBD2 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 22
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human
    Immunogen
    Recombinant human MBD2 between 10-228 amino acids.
    Klon
    G7R2
    Top Product
    Discover our top product MBD2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Andere Bezeichnung
    MBD2 (MBD2 Produkte)
    Synonyme
    MBD2 antikoerper, DMTase antikoerper, NY-CO-41 antikoerper, MBD2a antikoerper, wu:fa97f06 antikoerper, zgc:111862 antikoerper, methyl-CpG binding domain protein 2 antikoerper, methyl-CpG binding domain protein 2 S homeolog antikoerper, MBD2 antikoerper, Mbd2 antikoerper, mbd2 antikoerper, mbd2.S antikoerper
    Hintergrund

    Synonyms: Demethylase, DMTase, MBD 2, MBD2_HUMAN, MBD2a, Methyl CpG binding domain protein 2, Methyl CpG binding protein MBD2, Methyl-CpG-binding domain protein 2, Methyl-CpG-binding protein MBD2, NY CO 41.

    Background: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.

    Gen-ID
    8932
    UniProt
    Q9UBB5
    Pathways
    Chromatin Binding
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