IL23R Antikörper (AA 231-330) (HRP)

Produktnummer ABIN7091283

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IL23R in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IL23R Antikörper (AA 231-330) (HRP) (ABIN7091283)

Target: IL23R (Interleukin 23 Receptor (IL23R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL23R Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB)

Produktdetails anti-IL23R Antikörper (HRP)

Bindungsspezifität: AA 231-330

Kreuzreaktivität: Human

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-23R

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Details zu IL23R

Target: IL23R (Interleukin 23 Receptor (IL23R))

Andere Bezeichnung: IL-23R

Hintergrund:

Synonyms: IL23 Receptor, IL-23R, IL23R, interleukin 23 receptor, IL 23R, IL-23 receptor, IL23R_HUMAN, Interleukin-23 receptor.

Background: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Subunit : Heterodimer with IL12RB1. In presence of IL23, the heterodimer forms the IL23 receptor. Interacts with JAK2 and in presence of IL23 with STAT3.

Gen-ID: 149233

UniProt: Q5VWK5

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation